Keynote Presentation: Viral vectors – A manufacturer’s wish list

Gene delivery using Adeno- Associated Viruses has become the go to method for development for novel gene therapies. Numerous innovations have improved tissue targeting and gene expression, but innovations in the core AAV manufacturing process and in the characterization of these complex products are needed to improve productivity, consistency and enable processes to produce safer and more effective AAV products. I will outline a typical AAV manufacturing process and test methods and highlight areas where improvements and innovative solutions are needed.